Retinoids are substances similar in structure and function to retinol, including:

Cosmetic active ingredients such as retinoic acid (RA), isotretinoin, adapalene, and tazarotene;

Retinol, retinaldehyde, retinyl palmitate, retinyl propionate, retinyl retinoate, and above all, Hydroxypinacolone Retinoate, which is currently receiving attention. 

These substances can be chemically converted into each other, so there are conversion pathways.

When the body cannot absorb retinol and consume it, it converts it to retinyl palmitate and stores it. When needed, the palmitate bond is hydrolyzed by an esterase (the red location in the retinol ester structure diagram on the right is broken), releasing retinol. Retinol is oxidized by removing a hydrogen atom, becoming the intermediate retinaldehyde.

Retinaldehyde is further oxidized by adding an oxygen atom to form retinoic acid. Retinoic acid (tretinoin/retinoid) is the actual form of retinoid that enters the nucleus, binds to the trans-retinoin response element (RAR/RXR), and initiates the expression of the corresponding genes.

Why Choose Hydroxypinacolone Retinoate?

Are you looking to improve your skin's texture and appearance? Hydroxypinacolone retinoate might just be the solution you've been searching for. This innovative retinoid offers a range of benefits that set it apart from other retinoic acids and retinols on the market.

• Enhanced Stability of Hydroxypinacolone Retinoate: One of the key advantages of hydroxypinacolone retinoate is its superior stability compared to traditional retinoids. This means that it is less likely to degrade when exposed to light or air, ensuring that you get the full benefits of the product with each use.

• Hydroxypinacolone retinoate is Gentler on the Skin: Unlike some other retinoids that can cause irritation, redness, and peeling, hydroxypinacolone retinoate is known for being gentler on the skin. This makes it a great option for those with sensitive skin who still want to enjoy the benefits of a retinoid.
• Hydroxypinacolone retinoate has Increased Efficacy: Studies have shown that hydroxypinacolone retinoate is more effective at promoting collagen production and increasing cell turnover than traditional retinoids. This means that you can expect to see improvements in fine lines, wrinkles, and overall skin texture in a shorter amount of time.
• Hydroxypinacolone retinoate has a lower risk of sun sensitivity: One common side effect of using retinoids is increased sensitivity to the sun, which can lead to sunburn and other skin damage. Hydroxypinacolone retinoate has been shown to have a lower risk of causing sun sensitivity, making it a safer option for daytime use.
• Compatible with Other Skincare Ingredients: Hydroxypinacolone retinoate is known for being compatible with a wide range of other skincare ingredients, making it easy to incorporate into your existing routine. Whether you're using antioxidants, peptides, or hydrating ingredients, this retinoid is likely to play well with others.

With its enhanced stability, gentle nature, increased efficacy, lower risk of sun sensitivity, and compatibility with other skincare products, hydroxypinacolone retinoate stands out as a top choice for those looking to improve their skin's health and appearance. Consider adding this innovative retinoid to your skincare routine and experience the benefits for yourself.

This not only maintains the potent group of tretinoin but also binds directly to its receptor. It also covers the irritating group and enhances its physical and chemical stability.

Cosmetics containing HPR (hydroxypinacolone retinoate) VA are suitable for sensitive skin, but should not be used by pregnant women!